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Pain Syndromes:
Abdominal pain:
virtually any organ and structure within the abdomen may be a cause of
pain. Paramount is to make a proper diagnosis and treat early
potentially lethal disease. Abdominal pain that lasts for weeks requires
detective work. Systematically addressing every possible organ and
structure. Gallblader, pancreas, liver, esophagus, kidneys,
intestines need to be evaluated. Muscles covering the abdomen have also
been implicated in abdominal pain. Prior abdominal surgery may cause
internal adhesions and scar tissue leading to pain. At times, abdominal scars
may
trigger pain in certain individuals. Broken or injured ribs, need to be
evaluated as possible causes. Irritable bowel syndrome, ulcerative
colitis and Chron's disease are conditions involving the intestines. All
may present with abdominal pain. Abdominal masses and cancer should be
ruled out. Antineuropathics and
opioids may be used to help with pain. Your
doctor may recommend certain procedures that may help with diagnosis. If
pain improves after injecting the sympathetic chain with local
anesthetics then pain is assumed to be of sympathetic origin.
Further therapy will planned after.
Anal rectal pain:
rectal and anal pain could be devastating for patients. Pain may be due
to several causes, including trauma, infections, hemorrhoids, surgery
and colonoscopies. At times after exhaustive work-up, no reason is
found. Medications, acupuncture and nerve blocks could be used to
treat pain.
Ankylosing spondylitis:
Anterior Cutaneous nerve
entrapment syndrome
Arachnoiditis:
| Arachnoiditis describes a pain disorder caused by the
inflammation of the arachnoid, one of the membranes that
surround and protect the nerves of the spinal cord.
The arachnoid can become inflamed because of an
irritation from chemicals, infection from bacteria or
viruses, as the result of direct injury to the spine,
chronic compression of spinal nerves, or complications
from spinal surgery or other invasive spinal procedures.
Inflammation can sometimes lead to the formation of scar
tissue and adhesions, which cause the spinal nerves to
“stick” together. If arachnoiditis begins to interfere
with the function of one or more of these nerves, it can
cause a number of symptoms, including numbness,
tingling, and a characteristic stinging and burning pain
in the lower back or legs. Some people with
arachnoiditis will have debilitating muscle cramps,
twitches, or spasms. It may also affect bladder,
bowel, and sexual function. In severe cases,
arachnoiditis may cause paralysis of the lower limbs.
Arachnoiditis remains a difficult condition to
treat, and long-term outcomes are unpredictable.
Most treatments for arachnoiditis are focused on
pain relief and the improvement of symptoms that
impair daily function. A regimen of pain
management, physiotheraphy, exercise, and
psychotheraphy is often recommended. Surgical
intervention is controversial since the outcomes are
generally poor and provide only short-term relief.
Clinical trials of steroid injections and electrical
stimulation are needed to determine the efficacy of
these treatments.
Arachnoiditis appears to be a disorder that causes
chronic pain and neurological deficits and does not
improve significantly with treatment. Surgery may
only provide temporary relief. Aging and
pre-existing spinal disorders can make an accurate
prognosis problematic. The outlook for
someone with arachnoiditis is complicated by the
fact that the disorder has no predictable pattern or
severity of symptoms.
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Arthritis: Rheumatoid arthritis is disease that affects the joints.
It causes pain, swelling, and stiffness. If one knee or hand has
rheumatoid arthritis, usually the other does too. This disease often
occurs in more than one joint and can affect any joint in the body.
People with this disease may feel sick and tired, and they sometimes get
fevers.
Some people have this disease for only a few months, or
a year or two. Then it goes away without causing damage. Other people
have times when the symptoms get worse (flares), and times when they get
better (remissions). Others have a severe form of the disease that can
last for many years or a lifetime. This form of the disease can cause
serious joint damage.
Doctors don't know
the exact cause of rheumatoid arthritis. They know that with this
arthritis, a person's immune system attacks his or her own body tissues.
Researchers are learning many things about why and how this happens.
RA is treated by a
rheumathologist. If pain is severe, then NSAID's and opioids may
be of help. At times, selected joint injections, nerve blocks and
epidurals may be indicated.
Cancer pain: cancer
may be painful for several reasons. The tumor itself, growth into nearby
nerves, organs and tissue may all be responsible. Cancer may also
destroy the tissues after invading them, particularly painful when
involving bones and nerves. Tumor spread or metastases could be painful
for the same reasons explained. As a tumor grows, it may put pressure on
nerves, bones or other organs, causing pain.
Cancer therapy — such as chemotherapy, radiation and
surgery — may leave painful sequelae. After surgery,
recovery may be slow and painful. Radiation may burn
skin and other tissues. Chemotherapy can cause many
potentially painful side effects, including mouth sores,
diarrhea and nerve damage. Peripheral neuropathy after
chemotherapy could be difficult to treat.
There are many different ways to treat
cancer pain. Pain medications can
usually control the pain. Most commonly
used are NSAIDs, such as ibuprofen
(Advil), opioid medications, such as
codeine, morphine, oxycodone, fentanyl
or methadone. Severe cases may need
nerve blocks, epidurals and morphine
pumps. We may recommend a continuous
delivery of medication (epidural, spinal
or intravenous), and arrangements could
be made to receive these at home,
hospice or hospital.
Central Cord
Syndrome:
Central cord syndrome is
a form of incomplete
spinal cord injury (in
which some of the
signals from the brain
to the body are not
received), characterized
by impairment in the
arms and hands and, to a
lesser extent, in the
legs. The brain's
ability to send and
receive signals to and
from parts of the body
below the site of trauma
is affected but not
entirely blocked. This
syndrome, usually the
result of trauma, is
associated with damage
to the large nerve
fibers that carry
information directly
from the cerebral cortex
to the spinal cord.
These nerves are
particularly important
for hand and arm
function. Symptoms may
include paralysis and/or
loss of fine control of
movements in the arms
and hands, with
relatively less
impairment of leg
movements. Sensory loss
below the site of the
spinal injury and loss
of bladder control may
also occur, with the
overall amount and type
of functional loss
dependent on how
severely the nerves of
the spinal cord are
damaged.
There is no cure,
nor is there a
standard course of
treatment, for
central cord
syndrome. Drug
therapy, surgery,
and rest are often
part of the
treatment program.
The
prognosis for
individuals with
central cord
syndrome varies.
Patients who receive
medical intervention
soon after their
injury often have
good outcomes. Many
people with the
disorder recover
substantial function
after their initial
injury, and the
ability to walk is
recovered in most of
the cases, although
some impairment may
remain.
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Central pain syndrome:
Central pain syndrome is a
neurological condition caused by damage to or
dysfunction of the central nervous system (CNS), which
includes the brain, brainstem, and spinal cord. This
syndrome can be caused by stroke, multiple sclerosis,
tumors, epilepsy, brain or spinal cord trauma, or
Parkinson's disease. The character of the pain
associated with this syndrome differs widely among
individuals partly because of the variety of potential
causes. Central pain syndrome may affect a large portion
of the body or may be more restricted to specific areas,
such as hands or feet. The extent of pain is usually
related to the cause of the CNS injury or damage. Pain
is typically constant, may be moderate to severe in
intensity, and is often made worse by touch, movement,
emotions, and temperature changes, usually cold
temperatures. Individuals experience one or more types
of pain sensations, the most prominent being burning.
Mingled with the burning may be sensations of "pins and
needles;" pressing, lacerating, or aching pain; and
brief, intolerable bursts of sharp pain similar to the
pain caused by a dental probe on an exposed nerve.
Individuals may have numbness in the areas affected by
the pain. The burning and loss of touch sensations are
usually most severe on the distant parts of the body,
such as the feet or hands. Central pain syndrome often
begins shortly after the causative injury or damage, but
may be delayed by months or even years, especially if it
is related to post-stroke pain.
Pain medications often provide some reduction of
pain, but not complete relief of pain, for those
affected by central pain syndrome. Tricyclic
antidepressants such as nortriptyline or
anticonvulsants such as neurontin (gabapentin) can
be useful. Lowering stress levels appears to reduce
pain.
Information provided by
www.ninds.nih.gov/disorders/central_pain/central_pain.htm
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Cheiralgia paresthetica
Chronic Pain: While
acute pain is a normal sensation triggered in the nervous system to
alert you to possible injury and the need to take care of yourself,
chronic pain is different. Chronic pain persists. Pain signals keep
firing in the nervous system for weeks, months, even years. There may
have been an initial mishap -- sprained back, serious infection, or
there may be an ongoing cause of pain -- arthritis, cancer, ear
infection, but some people suffer chronic pain in the absence of any
past injury or evidence of body damage. Many chronic pain conditions
affect older adults. Common chronic pain complaints include headache,
low back pain, cancer pain, arthritis pain, neurogenic pain (pain
resulting from damage to the peripheral nerves or to the central nervous
system itself), psychogenic pain (pain not due to past disease or injury
or any visible sign of damage inside or outside the nervous system).
CRPS: complex regional
pain syndrome, formerly known as regional pain syndrome is a
constellation of symptoms involving usually extremities. The hallmark of
the condition is pain and inflammation that may progress to
complete loss of function of the limb. May be cause by a minor injury
like an ankle twist or more severe like bone fractures. Surgery, nerve
injury, burns, intramuscular injection have been implicated with this
condition. The initial injury may not be so small that it may not be
remembered by the patients. CRPS could be difficult to diagnose and may
go unrecognized until evaluated by the trained specialist. At times,
it is confused with early infection and time is wasted with antibiotic
therapy. Symptoms are exaggerated in relation to the suspected injury.
Therapy can be equally challenging. Tryciclic antidepressants,
anti-neuropathics are among the initial medications used. To help with
diagnosis, sympathetic blockade injections (neck or back) are given. If
injections are effective, it helps support the diagnosis. If pain is
difficult to control and medications and injections have failed to help,
then further therapy may include spinal cord stimulator and
intrathecal pumps.
Diabetic peripheral neuropathy:
progressive, painful condition of peripheral (usually arms and legs)
nerves. High levels of circulating sugars in blood are thought to cause
injury to nerves. The most important treatment is to maintain normal
levels of glucose in blood. Medications consider to be beneficial
include anticonvulsant and antidepressants. These include
tricyclic antidepressant like amitryptilin, nortryptiline and
desipramine. The most widely used anticonvulsant is gabapentin
(Neurontin). These medication may have side effects including dizziness,
difficulty concentrating, somnolence and loss of balance. This effects
will subside with time.
Eye pain: several
conditions may be associated with eye pain. Infections, trauma, surgery,
cancer and unknown causes. Different structures within the eye may
contribute to pain including the eye globe, eyelids, nerves,
arteries and muscles. Identifying the cause of pain becomes paramount in
treating the condition. Therapy is tailored to the cause. Your doctor
may choose a regimen including medications that treat neuropathic and
nerve pain, opioids or antidepressants. In selected cases injections may
be of benefit. Stellate ganglia blocks, nerve blocks may be offered.
Face pain: Several
conditions may be associated with face pain. Nerves, muscles, tendons an
bone may be implicated. Infections, herpes, trauma, nerve damage, stroke
and surgery may be a cause. Identifying the problem will help delineate
therapy. Your doctor may choose to trial antineuropathics, opioids,
antidepressant. If medications fail some injections may be of benefit
including stellate ganglia , trigger point, selected nerves (facial,
trigeminal, supraoptical etc), epidurals, TMJ and facet joints.
Fibromyalgia: very
complex medical condition, ignored by some; misunderstood by others. At
times, patients are not diagnosed and suffer for years. Tender muscles,
sleep disruption, morning fatigue and multiple other diffuse symptoms
hallmark fibromyalgia.Diagnosis is based on tenderness over specific
muscle areas and exclusion of other conditions. Therapy should be
multidisciplinary including physical therapy, reconditioning of fatigued
muscles, psychological support, control of depression and other
associated psychiatric symptoms. Medications that may be useful include
tryciclic antidepressants, antineuropathics, muscle relaxants, sleep aid
and trigger point injections. In some instances opioids may be used, but
rarely as a first option.
Headaches:
There are four types of headache: vascular, muscle
contraction (tension), traction, and inflammatory.
The most common type of vascular headache is migraine.
Migraine headaches are usually characterized by severe
pain on one or both sides of the head, an upset stomach,
and, at times, disturbed vision. Women are
more likely than men to have migraine headaches.
After migraine, the most common type of vascular
headache is the toxic headache produced by fever.
Other kinds of vascular headaches include "cluster”
headaches, which cause repeated episodes of intense
pain, and headaches resulting from high blood pressure.
Muscle contraction headaches appear to involve the
tightening or tensing of facial and neck muscles.
Traction and inflammatory headaches are symptoms of
other disorders, ranging from stroke to sinus infection.
Like other types of pain, headaches can serve as warning
signals of more serious disorders. This is particularly
true for headaches caused by inflammation, including
those related to meningitis as well as those resulting
from diseases of the sinuses, spine, neck, ears, and
teeth.
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Migraine
Moderate to severe pain — many migraine
headache sufferers feel pain on only one
side of their head, while some
experience pain on both sides. Feels
pulsating or throbbing, may worsen with
physical activity hindering
regular daily activities. Nausea with or
without vomiting is common. Also,
sensitivity to light and sound is
present.
Chronic tension-type headache
Occasional tension-type headaches sometimes progress to
daily attacks. The pain involves both sides of the head
and the back of the head and neck. It's often described
as a dull ache or a tight band of pressure around the
head. The pain may fluctuate throughout the day or be
steady for days, weeks or even years at a time.
New daily persistent headache
New daily persistent headaches begin abruptly in people
without a history of headaches. Sometimes the headaches
are triggered by an infection, surgery or stressful life
event, but often there's no recognized trigger. The pain
is often described as throbbing, dull, achy, stabbing or
burning, or as pressure or tightness. The pain continues
unabated throughout the day. Some new daily persistent
headaches go away within several months. Others persist
for years or even decades.
Hemicrania continua
Hemicrania continua is a relatively rare type of chronic
daily headache. The pain occurs on one side of the head
and varies in intensity without ever disappearing
completely. The pain is usually moderate but may include
jolts of severe pain that last less than a minute. The
flare-ups of severe pain may be accompanied by tearing
or redness of the eye on the affected side, swelling or
drooping of the eyelid, and a stuffy or runny nose. You
may experience nausea, vomiting and sensitivity to noise
and light. Sometimes auras — such as blind spots or
flashing lights in your visual field or sensations of
numbness or tingling — are present as well.
The causes of chronic daily headaches
are not well understood. For primary
chronic daily headaches, possible
factors may include:
- Medication overuse (Tylenol,
opioids)
- Muscle tension or tissue
inflammation.
- Abnormal function of brain
structures that suppress pain
- Changes in the nervous system
due to frequent headaches
- Stimulation of the central
nervous system due to stress,
infection or trauma
- Injury of the upper spine
- Vasculitis
- Tumors
- Infection
- Obstructive sleep apnea
Chronic daily headaches are more common
in women than in men. Various factors
may increase the chance of having
headaches, including:
- Anxiety
- Depression
- Sleep disturbances
- Obesity
- Snoring
- Overuse of caffeine
- Overuse of pain medication
When headaches occur three or more times
a month, preventive treatment is usually
recommended. Drug therapy,
biofeedback training, stress reduction,
and elimination of certain foods from
the diet are the most common methods of
preventing and controlling migraine and
other vascular headaches. Regular
exercise, such as swimming or vigorous
walking, can also reduce the frequency
and severity of migraine headaches.
Drug therapy for migraine is often
combined with biofeedback and relaxation
training. One of the most commonly
used drugs for the relief of migraine
symptoms is sumatriptan. Drugs
used to prevent migraine also include
methysergide maleate, which counteracts
blood vessel constriction; propranolol
hydrochloride, which also reduces the
frequency and severity of migraine
headaches; ergotamine tartrate, a
vasoconstrictor that helps counteract
the painful dilation stage of the
headache; amitriptyline, an
antidepressant; valproic acid, an
anticonvulsant; and verapamil, a calcium
channel blocker. Another
antidepressant — such as the selective
serotonin reuptake inhibitor (SSRI)
fluoxetine (Prozac) — may occasionally
be an effective alternative for some
people.
Muscle relaxants such as
tizanidine (Zanaflex) may help some
people manage chronic daily headaches.
Injections may be of benefit in certain
conditions. Trigger point injections in
tender muscles, nerve blocks
(trigeminal, facial, supraorbital) or
epidural steroid injections have been
used effectively. Severe cases can be
managed as in-patients in
multidisciplinary clinics.
For more information link to
http://www.ninds.nih.gov/disorders/headache/headache.htm
Low back pain: very
generalized term to characterize a group of conditions that produce back
pain. Several structures of the back may implicated in generating pain.
These include muscles, tendon, joints, nerves and spinal discs. It is
important to recognize the affected structure and minimize unnecessary
testing and therapy. Treatment can be as easy as muscle relaxants and
anti-inflammatory therapy. Well defined syndromes (and structures
causing pain) have been described: most commonly discogenic pain,
facet arthritis, myofascial pain, herniated discs, sciatic neuralgia,
sacro-iliitis, pirirformis syndrome and vertebral compression fractures.
- Herniated disc: the intervertebral disc
is a soft tissue, cushioning in between vertebral bones of the
spine. Trauma, age and arthritis may cause it to herniated ( squeeze
out of its capsule). Spinal nerves exit the spine in close proximity
to the disc and can be pinched by the squeezed disc. This creates a
local inflammation and irritation of the nerve. Spinal nerves give
origin to the large nerves of the leg, the most talked about being
the sciatic. From here derives the term “sciatica”.
Treatment consists of alleviating pain while allowing the herniation
to heal. Studies have shown that a disc herniation may resolve by
itself. Physical therapy, chiropractor care along with NSAID’s,
muscle relaxants and antineuropathics may be of benefit. Some
patients may need opioids. If this initial therapy fails the
epidural steroid injection may be needed. Epidural injections will
deliver anti-inflammatory medications very close to the nerve and in
turn decreasing pain. Very severe cases may need surgery.
- Sacro-iliitis: this joint is formed by
the sacrum and pelvis. Pain in felt in the low back, legs an groins.
Standing for too long and going from a sitting to a standing
position usually triggers pain. Physical therapy, stretch exercises
and chiropractor adjustments may be beneficial. Muscle
relaxants and NSAID’s are commonly used. Injection directed by
fluoroscopy (x-rays) into the joint may help relief pain.
- Discogenic pain: the vertebral disc
cushions in between two spine vertebrae. Disruption of its normal
anatomy may cause pain. Discomfort will be felt in the low back and
occasionally legs. It is important to promptly diagnose discogenic
pain to avoid unnecessary procedures and delay of treatment.
Epidural injections may be tried, if not effective then your doctor
may recommend a diagnostic procedure that consist of placing a
needle inside the disc and directly assessing the status of the disc
under fluoroscopy. Other therapies may include IDET and
nucleoplasty. Both procedures are performed by a pain specialist and
at times avoid surgery. A needle is placed in the disc and
small pieces are taken out or the disc is subjected to heat. Your
doctor will determine if you may be helped by these
procedures. Ultimately, surgery may be the only option.
- Piriformis Syndrome: aching
sore, shooting pain in the buttocks may be due to spasm of the
piriformis muscle. The sciatic nerves runs trough the muscle and may
be irritated by the muscle spasm. This condition may be confused
with sciatica and spinal nerve/disc herniation. It is important that
is properly diagnose to avoid unnecessary therapy, tests and pain.
Pain specialists are trained to recognize this condition. Therapy
consists of stretch exercises, muscle relaxants and injections into
the muscle. The muscle is located deep in the buttocks and x-rays
(fluoroscopy) should be used to confirm proper injection.
- Facet arthropathy: facet joints help
keep two vertebrae together. As other joints, the facets coordinate
movement of the spine. Pain is achy, sore, tender and diffuse. May
be worse in the morning, also presenting with stiffness. As the
joints “warm up” pain decreases, by the end of the day after sitting
and standing for too long, pain exacerbates. In certain cases, pain
may be felt radiating to the front and back of legs. This
pattern may be confuse with sciatica, the importance of being
evaluated by a trained pain specialist can not be stressed enough.
Treatments is aimed to decrease inflammation of the joints, promote
mobility and increase function. Physical therapy, coordinated
exercise, NSAID’s and the new COX 2 inhibitors (celebrex) are
cornerstone of therapy. Severe cases may need injections into the
nerve and/or facet rhizotomy (RFA)
- Vertebral fractures: caused by trauma
or bone weakening from osteoporosis. Extremely painful, at times
very difficult to treat. Potent opioids may be necessary to control
the pain. A relative new procedure places a needle into the bone,
and under close vigilance with fluoroscopy, cement is injected. When
dry, the cement will act as a cast inside the bone. Also, by filling
the vertebrae with cement, the normal anatomy may be restored.
- Myofascial pain: ilio-lumbaris,
paravertebral, multifidus are some of the examples of muscles
located on the low back. Spasm and injury of these and other muscles
may be severe enough to send patients to emergency rooms and primary
care doctors. Physical therapy, chiropractor adjustments, stretch
exercise and muscle relaxants are part of treatment. It is important
to be evaluated by trained pain MD’s to avoid unnecessary
tests and procedures.
Meralgia paresthetica:
condition associated with pain on the lateral aspect of the upper leg.
It presents with numbness and burning, shooting pain. Injury to the
lateral femoro-cutaneous nerve is consider the cause of this
syndrome. Obesity, wearing a heavy belt and trauma have been implicated
in injuring the nerve. Treatment include physical therapy, weight
loss and NSAID’s. In selected cases injections to the nerve with local
anesthetics and depo-medrol may be effective. If that fails, your doctor
may recommend epidural injections.
Myofascial Pain:
diffuse aching, sore and burning pain. May be throughout the body or
confined to a small group of muscles. This condition may present by
itself or associated with other syndromes like fibromyalgia and
arthritis. Treatment consist of muscle relaxants, trigger point
injections and physical therapy. Opioids are rarely effective.
Neck Pain: several
structures may be responsible for neck pain. Nerves, discs, tendons,
muscles and joints have all been reported as sources of pain. One or
several structures may be a cause of pain, complicating diagnosis and
treatment. Arthritis (facet joints), muscle spasm, disc herniations,
prior surgery, nerve impingement, neuralgias of the occipital nerve,
whiplash injuries, cancer, infection, spine trauma, vertebral
compression fractures, misalignment (anterolysthesis) and bleeding may
be possible etiologies.
Of paramount importance is to diagnose
infection, cancer, bleeding and fractures, as therapy may be more
effective early. Red flags help your doctor rule our these conditions:
pain worse at nights, fevers, chills, weight loss, loss of appetite,
insomnia, pain not resolving at rest. Treatment is oriented towards its
originating cause.
Once the above conditions are ruled out, a
systematic questioning and physical exam helps your doctor narrow the
potential sources of pain.
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Herniated discs may cause neck and arm pain.
Numbness, loss of sensation and weakness may be present. Pain may be
exacerbated with movement of the head, arms, coughing and sneezing.
Usually improved with rest.
-
Facet joint pain causes pain in the neck with
radiation to shoulders, posterior head and face. Much worse with
movement, better at rest. Pain radiating outside of the neck
confuses patients and doctors, focusing on mild disk disease. Often
misdiagnosing this easily treated condition.
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Muscles and tendons can be a significant source
of pain. Spasm may occur after accidents, falls or poor positioning
at work. At times muscle spasms occur as a response of the body to
changes in posture when pain is present from other causes.
-
Nerve (non spinal) damage can occur after
falls, whiplash injury and poor positioning. pain is diffuse, aching
and burning. Difficult for patients to describe. Poor localization
of pain is also common.
Herniated discs could be treated initially
conservatively with medications, chiropractor care, physical therapy,
acupuncture and epidural injections. Contained disc herniations
may respond to decompression of the disc via a needle. Also called
percutaneous discectomy. Surgery may be indicated for severe
cases, particularly those affecting mobility of arms, loss of sensation
and increasing pain. Muscle and tendon pain respond well to muscle
relaxants, myofascial release therapy, physical therapy, trigger points
injections and acupuncture. For vertebral fracture treatment see:
vertebroplasty. Facet joint or arthritic pain is treated with NSAID's,
Physical therapy, chiropractor care and acupuncture. Severe cases may
respond to facet joint injections or ablation of the nerve feeding the
joint. This procedure (See procedures for more information), may improve
pain for up to one year. Neuralgias to specific nerves or group of
nerves (occipital, superficial cervical plexus) responds to medications,
injections and physical therapy.
Occipital Neuralgia:
pain confined to posterior head. With a diffuse, throbbing, sharp and
aching nature. Extreme tenderness upon palpation help with diagnosis. A
simple injection performed in the office with local anesthetics into the
nerve helps confirm the diagnosis. Therapy involves TCA's and
antineuropathics. Further therapy include injecting with depo-medrol and
sarapin.
Pancreatitis:
inflammation of the pancreas. When acute, it should resolve on its own,
and rarely pain medications are needed. Cancer and chronic disease may
come with constant severe pain. Opioids and antineuropathics should
initially help. If severe and not responding then epidural injections,
sympathetic blocks may be needed. Lastly, if all fails spinal pumps and
epidural catheters may be placed to provide with constant potent
medications directly to the spine and near the pancreas.
Pelvic pain: very
complicated condition affecting both men and women. An extensive list of
conditions may be responsible for causing pain in the pelvic region.
Cancer, tumors, endometriosis, dysmenorrhea, infections, nerve damage,
trauma, surgery, psychological conditions, fibromyalgia, colo-rectal
disease, menstrual period need all be evaluated as causes of pelvic
pain. After no surgical or treatable cause is identified your pain
doctor may recommend a medical regimen as initial therapy. Acupuncture
may be effective in certain cases. Epidural injections, sympathetic
blocks may also be tried. Some of these injections can be done in an
office setting. If scars are present in the area they may need to be
injected, as scars are a common source of pain. For severe, intractable
cases more invasive therapies can be suggested by your pain doctor.
Peripheral neuropathy:
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Peripheral neuropathy describes damage
to the peripheral nervous system, which
transmits information from the brain and
spinal cord to every other part of the
body. More than 100 types of peripheral
neuropathy have been identified, each
with its own characteristic set of
symptoms, pattern of development, and
prognosis. Impaired function and
symptoms depend on the type of nerves --
motor, sensory, or autonomic -- that are
damaged. Some people may
experience temporary numbness, tingling,
and pricking sensations, sensitivity to
touch, or muscle weakness. Others may
suffer more extreme symptoms, including
burning pain (especially at night),
muscle wasting, paralysis, or organ or
gland dysfunction. Peripheral neuropathy
may be either inherited or acquired.
Causes of acquired peripheral neuropathy
include physical injury (trauma) to a
nerve, tumors, toxins, autoimmune
responses, nutritional deficiencies,
alcoholism, and vascular and metabolic
disorders. Acquired peripheral
neuropathies are caused by systemic
disease, trauma from external agents, or
infections or autoimmune disorders
affecting nerve tissue. Inherited forms
of peripheral neuropathy are caused by
inborn mistakes in the genetic code or
by new genetic mutations.
No medical treatments exist that can
cure inherited peripheral
neuropathy. However, there are
therapies for many other forms.
In general, adopting healthy habits
-- such as maintaining optimal
weight, avoiding exposure to toxins,
following a physician-supervised
exercise program, eating a balanced
diet, correcting vitamin
deficiencies, and limiting or
avoiding alcohol consumption -- can
reduce the physical and emotional
effects of peripheral neuropathy.
Systemic diseases frequently require
more complex treatments.
Anti-neuropathics are commonly used
as therapy. For severe cases,
temporary relief may be achieved
with epidural steroid injections.
Some types of peripheral
neuropathies respond to spinal cord
stimulators and intrathecal pumps.
In acute neuropathies, such as
Guillain-Barré syndrome, symptoms
appear suddenly, progress rapidly,
and resolve slowly as damaged nerves
heal. In chronic forms, symptoms
begin subtly and progress slowly.
Some people may have periods of
relief followed by relapse. Others
may reach a plateau stage where
symptoms stay the same for many
months or years. Some chronic
neuropathies worsen over time, but
very few forms prove fatal unless
complicated by other diseases.
Occasionally the neuropathy is a
symptom of another disorder.
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Adapted from
www.ninds.nih.gov/disorders/peripheralneuropathy/peripheralneuropathy.htm |
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Phantom pain: see
post-amputation pain. Phanton limb syndrome is pain of an amputated limb
(finger, toes, arms, legs).
Piriformis syndrome:
aching sore, shooting pain in the buttocks may be due to spasm of the
piriformis muscle. The sciatic nerves runs trough the muscle and may be
irritated by the muscle spasm. This condition may be confused with
sciatica and spinal nerve/disc herniation. It is important that is
properly diagnose to avoid unnecessary therapy, tests and pain. Pain
specialist are trained to recognize this condition. Therapy consist of
stretch exercises, muscle relaxants and injections into the muscle. The
muscle is locate deep in he buttocks and x-rays (fluoroscopy) should be
used to confirm proper injection.
Plantar fasciitis:
Post-surgery knee pain:
constant burning, shooting and aching pain after knee surgery may be the
result of damage to saphenous and peroneal nerves. Therapy consists of
antineuropathics and blocking the affected nerves. Opioids are rarely
effective, but may be tried. Differentiating this pain from other common
pain syndromes is key, other possible diagnosis may include CRPS, spinal
nerve damage from a herniated disck or infections. It is important to be
seen by a physician trained in recognizing these conditions.
Post-laminectomy pain syndrome:
common term to refer to pain in the back and extremities after surgery.
Pain may originate from screws and hardware placed in the spine, nerve
damage after surgery, scar tissue surrounding nerves and free moving
disc or bone fragments. It is paramount that a spine surgeon rules out a
surgical cause for the pain. Although pain started after surgery,
further surgery may be the only solution. Antineuropathics and judicious
amounts of opioids may be prescribed. Acupuncture has shown to be
effective in certain cases. Severe pain, not improving with conservative
therapies, may necessitate intrathecal pumps or spinal cord stimulators.
Post lumpectomy pain:
see mastectomy pain syndrome.
Post herpetic neuralgia:
Shingles (herpes zoster) is an
outbreak of rash or blisters on the skin that is caused
by the same virus that causes chickenpox — the
varicella-zoster virus. The first sign of shingles is
often burning or tingling pain, or sometimes numbness or
itch, in one particular location on only one side of the
body. After several days or a week, a rash of
fluid-filled blisters, similar to chickenpox, appears in
one area on one side of the body. Shingles pain can be
mild or intense. Some people have mostly itching; some
feel pain from the gentlest touch or breeze. The most
common location for shingles is a band, called a
dermatome, spanning one side of the trunk around the
waistline. Anyone who has had chickenpox is at risk for
shingles. Scientists think that in the original
battle with the varicella-zoster virus, some of the
virus particles leave the skin blisters and move into
the nervous system. When the varicella-zoster
virus reactivates, the virus moves back down the long
nerve fibers that extend from the sensory cell bodies to
the skin. The viruses multiply, the tell-tale rash
erupts, and the person now has shingles.
The severity and duration of an attack of
shingles can be significantly reduced by immediate
treatment with antiviral drugs, which include
acyclovir, valcyclovir, or famcyclovir. Antiviral
drugs may also help stave off the painful
after-effects of shingles known as postherpetic
neuralgia. Other treatments for postherpetic
neuralgia include steroids, antidepressants,
anticonvulsants, and topical agents. When pain is
severe, epidural injections may be effective.
Intractable cases may necessitate further invasive
therapy. Consult a fellowship trained pain physician
For more information check
www.ninds.nih.gov
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Post mastectomy pain:
breast surgery may injure a local nerve, the intercosto-brachialis. Pain
is felt around the breast, axilla and sometimes chest. Therapy consist
of mainly antineuropathics. Opioids may betried in severe cases. Some
blocks may be of benefit. If all fails, then spinal cord stimulator and
spinal pumps may be tried.
Post radical neck dissection
pain: radical neck dissection surgery may be necessary to
remove cancer lesions from neck, face and throat. In the process,
unfortunately a group of nerves called superficial cervical plexus may
be injured. Pain is localized to the side of surgery. Usually burning an
throbbing in nature. Medications may be tried initially, consisting of
antineuropathic kind. Injecting the plexus may provide pain control.
This is an easy, safe injection. May be performed in the office setting.
Post thoracothomy pain syndrome:
after chest surgery (CABG, cancer, biopsy) the intercostals nerves may
be injured. Pain slowly progresses after surgery and is localized on
the side of surgery. Early therapy with antineuropathics, intercostals
injections and epidural may help worsening of symptoms. Delaying therapy
makes it more difficult to treat this condition. In very severe cases
spinal cord stimulator or a spinal pump may be the only option.
Post-amputation pain:
pain may originate from the missing limb (AKA phantom limb pain) or from
the stump. In both cases the origin of pain is nerve structures. Therapy
consists of antineuropathics, injections into the affected nerves and
epidurals. Severe cases may require a spinal pump or spinal cord
srimulator.
Post-chemotherapy peripheral
neuropathy: see peripheral neuropathy. Treatment of cancer
with certain agents may injure peripheral nerves causing severe,
burning, electrical type of pain. Treatment is described in
peripheral neuropathy.
Post-stroke pain: see
central pain.
Prostadynia
Pudendal neuralgia:
Painful condition involving the pudendal nerve affecting both men and
women. The pudendal nerve runs through the pelvic region, including
genitals,
urethra,
anal, and
perineum.
Your perineum is the area between your anus and genitals. The condition
is also known as pudendal neuropathy, pudendal nerve entrapment,
cyclist's syndrome, pudendal canal syndrome, or Alcock’s syndrome.
Pudendal neuralgia can cause pain, especially when
one sits. Men with pudendal neuralgia may have pain in the buttocks,
scrotum,
penis, and perineum. Women with pudendal neuralgia may have pain in
their buttocks,
vulva,
urethra, and perineum.
If the pudendal nerve is entrapped,
surgery may be needed to free the nerve. For other causes acupuncture,
medications and biofeedback often improve pain. Severe cases may
need nerve injections, epidural injections or sympathetic blocks may be
needed. Spinal cord stimulators have been used for intractable,
debilitating pain.
Radiation enteritis
Raynaud’s syndrome:
disease of the collagen system. Involves damage to arteries causing low
flow of blood to hands. Lack of oxygen to nerves in hands may cause
severe pain. Severe cases may improve with sympathetic nerve blocks and
spinal cord stimulators.
RSD: see CRPS.
Scar neuroma: skin
scars are thought to cause pain by entrapping small nerves within. Very
simple therapy performed in the office may diagnose and at the same time
treat the pain.
Slipping rib syndrome
Spinal cord injury pain:
see Central Cord Syndrome.
Spondylolisthesis:
term that defines the slippage of one vertebrae over the next one. All
structures contained within will be strained with the movement of the
two vertebrae. Early cases can be treated conservatively with
chiropractor care, physical therapy and medications. More severe cases
may need surgical repair. See back pain above.
Stump pain: pain
originating after amputation. Usually results from scar neuromas or
nerve pain. Pain that continues several weeks after surgery may need
intervention. Medications, acupuncture, nerve blocks or sympathetic
blocks may be recommended by your doctor. Severe cases have
responded in the past to spinal cord stimulators.
Temporal arteritis:
Vasculitis is an inflammation of
the blood vessel system, which includes the veins,
arteries, and capillaries. Vasculitis may affect blood
vessels of any type, size, or location, and therefore
can cause dysfunction in any organ system, including the
central and peripheral nervous systems. The symptoms of
vasculitis depend on which blood vessels are involved
and what organs in the body are affected. The disorder
may occur alone or with other disorders such as temporal
arteritis. Temporal arteritis (also called cranial or
giant cell arteritis) is an inflammation of the temporal
artery (which runs over the temple, beside the eye).
Symptoms of this disorder may include stiffness, muscle
pain, fever, severe headaches, pain when chewing, and
tenderness in the temple area. Other symptoms may
include anemia, fatigue, weight loss, shaking, vision
loss, and sweats.
Treatment for vasculitis depends on the severity of the disorder and
the individual's general health. Treatment may include cortisone or cytotoxic
drugs. Other treatments may include plasmapheresis (the removal and reinfusion
of blood plasma), intravenous gammaglobulin, and cyclosporin. Some cases of
vasculitis may not require treatment. Treatment for temporal arteritis and its
associated symptoms generally includes corticosteroid therapy. Early detection
of temporal arteritis and immediate treatment are essential to prevent vision
loss.
The prognosis for individuals with vasculitis varies
depending on the severity of the disorder. Mild
cases of vasculitis are generally not
life-threatening, while severe cases (involving
major organ systems) may be permanently disabling or
fatal. The prognosis for individuals with temporal
arteritis is generally good. With treatment, most
individuals achieve complete remission, however
vision loss may be irreversible.
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Tendinitis
Testicular pain
Torticollis
Trigeminal neuralgia
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Trigeminal neuralgia (TN), also called tic douloureux,
is a chronic pain condition that causes extreme,
sporadic, sudden burning or shock-like face pain that
lasts anywhere from a few seconds to as long as 2
minutes per episode. The intensity of pain can be
physically and mentally incapacitating. TN pain is
typically felt on one side of the jaw or cheek. Episodes
can last for days, weeks, or months at a time and then
disappear for months or years. In the days before
an episode begins, some patients may experience a
tingling or numbing sensation or a somewhat constant and
aching pain. The attacks often worsen over time,
with fewer and shorter pain-free periods before they
recur. The intense flashes of pain can be
triggered by vibration or contact with the cheek (such
as when shaving, washing the face, or applying makeup),
brushing teeth, eating, drinking, talking, or being
exposed to the wind. TN occurs most often in
people over age 50, but it can occur at any age, and is
more common in women than in men. There is some
evidence that the disorder runs in families, perhaps
because of an inherited pattern of blood vessel
formation. Although sometimes debilitating, the disorder
is not life-threatening.
The presumed cause of TN is a blood vessel pressing on
the trigeminal nerve in the head as it exits the
brainstem. TN may be part of the normal aging process
but in some cases it is the associated with another
disorder, such as multiple sclerosis or other disorders
characterized by damage to the myelin sheath that covers
certain nerves.
Because there are a large number of conditions that
can cause facial pain, TN can be difficult to
diagnose. But finding the cause of the pain is
important as the treatments for different types of
pain may differ. Treatment options include
medicines such as anticonvulsants and tricyclic
antidepressants, surgery, and complementary
approaches. Typical analgesics and opioids are not
usually helpful in treating the sharp, recurring
pain caused by TN. If medication fails to
relieve pain or produces intolerable side effects
such as excess fatigue, surgical treatment may be
recommended. Several neurosurgical procedures are
available. Some are done on an outpatient basis,
while others are more complex and require
hospitalization. Some patients choose to manage TN
using complementary techniques, usually in
combination with drug treatment. These
techniques include acupuncture, biofeedback, vitamin
therapy, nutritional therapy, and electrical
stimulation of the nerves.
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Trigger finger
Vaginal pain
Vascular Ischemic pain:
lack of blood flow to extremities contributes pain in lower extremities.
Pain is usually worse with walking and improves with rest. If surgery
has failed to improve blood flow. Pain can be controlled with
medications. Acupuncture may be tried. More invasive procedures could be
indicated in severe cases. Placement of stimulators in the epidural
space may increase the blood flow to lower extremities.
Vertebral fracture:
caused by trauma or bone weakening from osteoporosis. Neck, upper and
lower back may be affected. Extremely painful, at times very difficult
to treat. Potent opioids may be necessary to control the pain. A
relative new procedure places a needle into the bone, and under close
vigilance with fluoroscopy, cement is injected. When dry, the cement
will act as a cast inside the bone. Also, by filling the vertebrae with
cement, the normal anatomy may be restored.
Vulvodinia
Winged scapula syndrome
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